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Despite their effectiveness, concerns remain regarding safety, tolerability and potential health risks, as well as the need for long-term administration and the subsequent cost

2.1.3 Endpoints and Statistical Analysis A sample size of 35 (14 with normal renal function and 7 in each of the renal impairment groups) was chosen

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These high-resolution spatial transcriptomics maps provide further support for the conclusions from the scRNA-seq results that a senescent-like MuSC and progenitor cell population is more abundant in the geriatric mice, suggesting stalled stem cell self-renewal in aging