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All parameters were compared with those of healthy mice individually using the one-way analysis of variance (ANOVA) test

GPR does not assume a fixed functional form but instead relies on the data itself to infer patterns, which makes it highly flexible and adaptable to complex relationships 53,54

& Chen, R

It follows that a defect in this process can propagate LTSC of pain, causing clinically identifiable chronic pain

This means that a peptide with a 2-hour half-life administered three times daily will reach steady-state within approximately 10 hours, while a peptide with a 7-day half-life like Semaglutide requires roughly 35 days to reach steady state with weekly dosing