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5.9 Neuromyelitis optica spectrum disorders A first-in-human clinical study of CT103A indicated that BCMA CAR T-cell therapy resulted in improvements in disability and quality of life outcomes, a reduction in AQP-4 antibodies, and a manageable safety profile in patients with relapsed or refractory AQP4-IgG seropositive neuromyelitis NMOSD (134)

doi: 10.1089/ars.2010.3211

Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes

Les taches pigmentaires peuvent apparatre la suite d'imperfections, de frottements rpts ou d'une exposition excessive au soleil

Even at labeled dosage regimens, individuals who are ultra-rapid metabolizers may have life-threatening or fatal respiratory depression or experience signs of overdose (such as extreme sleepiness, confusion, or shallow breathing) [see OVERDOSAGE]