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Interaction between the non-catalytic cysteine at position 129 and the catalytic cysteine 227 shows the formation of a disulfide bond, which maintains its catalytic activity (91, 92)

Aside from hyperactivity, SHR rats are readily reported to exhibit low level of spontaneous alternation behavior in the Y-maze test [41, 42]

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3a and Supplementary Data 2), whereas in ncl-1 RNAi exposed nematodes, the downregulation of VITs was less pronounced and ribosomal content became moderately upregulated with age (Fig