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A recent study demonstrated the ability of a dendrimer-conjugated NAC (D-NAC) to specifically target glial and astrocyte cells, indicating potential to alter GSH levels in specific cell populations without altering levels throughout the CNS (Nance et al., 2017

Metabolic effects of Lactobacillus reuteri DSM 17938 in people with type 2 diabetes: a randomized controlled trial

Watanabe T, Sagisaka H, Arakawa S, Shibaya Y, Watanabe M, Igarashi I, Tanaka K, Totsuka S, Takasaki W, Manabe S: A novel model of continuous depletion of glutathione in mice treated with L-buthionine (S,R)-sulfoximine

The mass accuracy was set to 15 ppm, and the precursor FDR allowed was 0.01 (1%)

Methionine is an essential amino acid, and selenium is an antioxidant that acts as a cofactor for glutathione peroxidase which neutralizes hydrogen peroxide (see Figure 1)