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It is unclear whether the peptide may affect insulin resistance, water retention, joint pain, or muscle pain which are usually related to hGH abuse

The medication binds to specific receptors in your pancreas, brain, and digestive tract

study demonstrated that ipamorelin: Released GH in a dose-dependent manner Did not significantly elevate cortisol levels, even at high doses Did not significantly elevate prolactin levels Did not significantly affect ACTH, FSH, LH, or TSH (4) This selectivity gives ipamorelin a notably clean side-effect profile compared to other GH secretagogues

None of the three compounds have human safety data in pregnancy or breastfeeding, and they are not FDA-approved

Some research suggests DSIP effects may persist for multiple nights after dosing [2]