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For this purpose, activation of adaptive stress responses was investigated for DNA damage (p21), oxidative stress (SRXN1), inflammation (ICAMI), and ER stress (CHOP) using a HepG2-based GFP-reporter assay (Wink et al., 2014, 2017)

Pyroglutamic acidosis by glutathione regeneration blockage in critical patients with septic shock

Briefly, the middle 10 cm of small intestine was collected 1 h after the seventh OVA gavage, and flushed once intraluminally with PBS, and then once with 10% NBF

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Although other types necrotic cell death such as pyroptosis and necroptosis are mediated by the formation of membrane pore, ferroptosis is believed to result from the accumulation of unrepaired cell damage [70]