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The most commonly reported effects include injection site reactions (redness, mild swelling, itching), joint pain or stiffness, numbness or tingling in the extremities (paresthesia), headaches, and mild fluid retention

[24] In the 1980s-2000s, its practitioners estimated that between 100,000 and 200,000 Americans per year were undergoing chelation therapy for heart disease, at a cost of about $5,000 per course of treatment

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