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& Al-Chalabi, A

Mechanism of action and the biological activities of Nigella sativa oil components

This is supported by the finding that oral supplementation of a single load of glutamate (6g) in healthy lactating women did not alter levels of any of the FAAs in their breastmilk (72)

Patients who should NOT use it include those with uncontrolled diabetes, active malignancy or personal history of hormone-sensitive cancer, or pituitary disease

Although the antifungal agent Shikonin shows potential, its clinical use is limited due to poor tumor specificity, low water solubility, short bloodstream half-life, and high risk of side effects on healthy tissues (Boulos et al., 2019)