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Product Information Chemical Data Analyte Name Glutathione Ammonium Salt-d5 Molecular Formula C10H12D5N3O6S (free acid) SMILES O=C(O)CNC([C@H](CS)NC(C([2H])([2H])C([2H])([2H])[C@]([2H])(N)C(O)=O)=O)=O InChI InChI=1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1/i1D2,2D2,5D Unlabelled CAS Number 70-18-8 Product Data Storage Temperature -20C Shipping Temperature Room Temperature Product Type Stable Isotope Labelled

In recent years, a large body of evidence has shown that protective autophagy, cell cycle regulators, and some transcription factors play a key role in tamoxifen resistance, such as KLF4 regulating drug resistance by regulating MAPK and the discovery of LEM4 (Gao et al., 2018

The development of HCC is further promoted by enhanced glycolysis resulting from elevated PGAM1 protein levels [28]

10.1016/j.theriogenology.2008.12.015 2

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