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These cells turn out to produce a number of IGFBPs under certain circumstances and it is known that this protein drastically lowers the impact of IGF-1 at its other receptors

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Additionally, a case study reports the first case of chronic pancreatitis associated with mitochondrial encephalopathy, linked to the A8344G mtDNA mutation, highlighting the potential role of mitochondrial dysfunction in recurrent pancreatitis (156)

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