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As a result, GO provides a specialized microenvironment where typically immiscible reagents can come together and undergo chemical reactions 278

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That includes in-utero immune activation (e.g., fever/infections), maternal health , medication use , nutrition , and co-exposures all unfolding against the backdrop of a childs unique genetic makeup

If a condition was 100 percent genetic, there would be a concordance rate of 100 percent in identical twins