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Description

Exome sequencing in Asian populations identifies low-frequency and rare coding variation influencing Parkinsons disease risk

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Autophagy-mediated ferritin degradation, facilitated by the cargo receptor NCOA4, enhances ferroptosis, while decreased NCOA4 expression lowers cellular GSH levels and increases susceptibility [58]

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The PVDF membranes were blocked with 5% nonfat milk for 1.5 h and then incubated overnight at 4 C with the following primary antibodies: anti-TNF- (Abcam, ab300093), anti-NLRP3 (Abcam, ab254360), anti-BDNF (Abcam, ab108319), anti-Synaptophysin (SYP) (Abcam, ab156302) and anti-PSD95 (Abcam, ab238135)

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doi: 10.1096/fj.14-269811 87

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