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The deficits in lipid metabolism that make schistosomes dependent on the host are revealed, and the identification of membrane receptors, ion channels and more than 300 proteases provide new insights into the biology of the life cycle and new targets

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In addition, INH was found to disturb the homeostasis of endogenous metabolites, such as vitamin B6, bile acids, cholesterol, and triglycerides21, 61, 62

The combination of AOD9604 with HA was more effective than either treatment alone, suggesting a synergistic interaction