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FcRn-dependent IgG accumulation in adipose tissue unmasks obesity pathophysiology

New research presented at the Endocrine Societys 2025 Annual Meeting (ENDO 2025) has revealed that tirzepatidea medication originally developed for weight loss and type 2 diabetesmay offer surprising benefits for men suffering from both obesity and functional hypogonadism (low testosterone due to metabolic causes)

Requests for data that underpin the findings reported in this article may be made to the corresponding author, subject to adherence to participant confidentiality and ethical considerations