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Intrinsic factor (IF) by parietal cells travels with the protein-bound vitamin B12 to the small intestine, where the higher pH facilitates hydrolysis of R protein to vitamin B12, which allows vitamin B12 to bind with IF

Keatings lab is also designing peptides that could interfere with other relatives of Mcl-1, including one called Bfl-1, which has been less studied than the other members of the family but is also involved in blocking apoptosis

This population of senescent-like MuSCs increases within the injury zone and in older mice, suggesting that a stalled stem cell self-renewal state underlies the regenerative dysfunction in mouse aging

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