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PMID 21422060

The antioxidant property of Sp was however, found to be insensitive to depletion of glutathione by BSO, which generally causes loss of cellular antioxidant function and higher ROS (Fig

Impaired gut integrity is critical for the participation of microbiota in aging, heat-killed Lactobacillus paracasei D3-5 (D3-5) reduces age-related intestinal leakage and inflammation, prevents metabolic dysfunction, and enhances physical function in aged mice (Wang et al., 2020)

Taken together, these data establish a clinically relevant warning: in a TAMs-rich tumor such as ovarian cancer, ferroptosis-based interventions must be evaluated not only by tumor-cell killing but by the macrophage phenotype they induce [114,115]