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Following iron replacement, one can begin to see a rise in the hemoglobin in 2-4 weeks

To illustrate, such a mechanism could lead to the activation of the transcription factor nuclear factor erythroid 2-related factor 2 (Nrf2), as suggested by Ohta (2023), which is known to be involved in oxidative stress responses (Yu et al., 2021) and involves a basic leucine zipper (bZIP) transcription factor