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However, developing engineered microbes as live biotherapeutic products presents considerable challenges in regulatory affairs, manufacturing, genetic stability, biocontainment, delivery, engraftment, and overall safety (135)

doi: 10.1002/sca.21326

This effect limits leukocyte adhesion and attenuates vascular inflammation (81)

doi: 10.3389/fimmu.2025.1509131 Received 10 October 2024 Accepted 19 March 2025 Published 03 June 2025 Volume 16 - 2025 Edited by Carlos Manuel Zapata-Martn del Campo, National Institute of Cardiology Ignacio Chavez, Mexico Reviewed by Robet L

Animal studies have demonstrated that the supplementation of CoQ10 in vitro during the culture of embryos significantly enhances the cleavage rate, blastocyst formation rate, hatching rate, and blastocyst expansion rate of early embryos (Xu et al., 2018)