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On the other hand, they reduce levels of pro-inflammatory cytokines such as TNF- and IL-6, as well as oxidative stress markers like MDA

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It helps neutralize free radicals, supports the immune system, and is involved in various cellular processes

Reduced activities of other enzymatic antioxidants namely, catalase and glutathione peroxidase (GPx) were also reported in peptic ulcer patients suggestive of enhanced free radical activity in acid-peptic disorders [23]

This discrepancy could be because the lower levels of MGMT methylation found in most HCC samples outweigh the relatively small proportion of increase in MGMT hypermethylation occurring in alcohol-associated HCC [108]