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doi: 10.3389/fnagi.2022.804890 356 WaxmanS

Omega-3 PUFAs originate from alpha-linolenic acid (ALA), while omega-6 PUFAs come from linoleic acid (LA)

FBS 20% DMSO was slowly added dropwise to the cell suspension for a final concentration of FBS 10% DMSO

COMT inhibitors (e.g., entacapone, tolcapone, opicapone) prolong levodopa's halflife by preventing its peripheral degradation, increasing its availability in the brain, and enhancing the duration of dopamine action [6]

Research should be committed to the development of combination therapies, integrating ferroptosis inducers with traditional chemotherapy, radiotherapy, targeted therapy, or immunotherapy to enhance therapeutic effects and reduce the resistance associated with monotherapy