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doi: 10.1049/icp.2024.2526 29
Symptoms of B12 Deficiency If left untreated, a B12 deficiency can lead to several serious symptoms , including: Fatigue and weakness Pale or jaundiced skin Numbness or tingling in hands and feet (due to nerve damage) Difficulty walking , balance problems Memory problems , difficulty concentrating (brain fog) Mood changes , such as depression or irritability Glossitis (inflammation of the tongue) and mouth sores Shortness of breath and dizziness (due to anemia) Heart palpitations B12 injections are the fastest and most effective way to treat a Vitamin B12 deficiency because they deliver the vitamin directly into the bloodstream, bypassing the digestive system
References Nature Medicine (2014) Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity View Source PMC (2024) Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunctions View Source Frontiers in Pharmacology (2024) NNMT: a novel therapeutic target for metabolic syndrome View Source PubMed (2021) LC-MS/MS assay for 5-amino-1-methylquinolinium: pharmacokinetic and oral bioavailability study View Source ResearchGate (2021) Combined NNMT inhibition and reduced-calorie diet normalizes body composition in obese mice View Source PMC (2022) Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice View Source NMN.com / Scientific Reports Role of NNMT inhibition in muscle strength: enhanced grip strength with exercise View Source Swolverine 5-Amino-1MQ mechanism, benefits, stacking and cycling guide View Source PMC Subcutaneous drug injection review: pharmacologic considerations View Source CDC Vaccine administration: subcutaneous route (angle/site
More extensive, well-designed research is needed before definitive statements can be made
