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Recent advancements further highlight TMAOs role in activating PERK across diverse tissues

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doi: 10.1210/jc.2010-0191 53 StrangesSMarshallJRNatarajanRDonahueRPTrevisanMCombsGFet al

Antibodies can directly bind to a region of a pathogen or toxin that is used for cellular entry ( Figure 1B )

ROS contributes to the activation of NF-B, which is responsible for regulating inflammatory mediators such as TNF [58]

Additionally, the GSH content was significantly reduced in the substantia nigra of PD patients, suggesting that GSH depletion enhances neuronal death under certain pathological conditions [6]