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Interestingly, in contrast with cytosolic, the membrane-associated GSTP1 had no detectable catalysis of CDNB conjugation with GSH

Effect of semaglutide on kidney function across different levels of baseline HbA1c, blood pressure, body weight and albuminuria in SUSTAIN 6 and PIONEER 6

Drug repurposing for metabolic targeting Repurposing FDA-approved drugs with known metabolic effects for cancer treatment offers several advantages: established safety profiles, known pharmacokinetics, reduced development timelines, and lower costs compared to de novo drug development

Naqvi S, Kim S, Tabatabaee S, Pampari A, Kundaje A, Pritchard JK

It's important to understand what reactions can occur so that appropriate action can be taken if they do arise