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Most patients tolerate this without issue, but if you go into surgery with a reduced red cell count, your oxygen-carrying capacity is already compromised before the incision is made

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Of the 2,570 MOUNJARO-treated patients who developed anti-tirzepatide antibodies during the treatment periods in these seven trials, 2% and 2% developed neutralizing antibodies against tirzepatide activity on the GIP or GLP-1 receptors, respectively, and 0.9% and 0.4% developed neutralizing antibodies against native GIP or GLP-1, respectively

Once the stores have been replaced then only maintenance injections will be required, depending on the reasons for the deficiency