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In high L-arginine-dependent tumors, such as breast cancer (Abdelmagid et al., 2013), and HCC (Kishikawa et al., 2015), increased expression of the transporter CAT-1 ( SLC7A1 ) has been observed, and CAT-1 ( SLC7A1 ) knockdown decreases the viability of cancer cells and induces apoptosis

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4d), suggesting that the functions of LDHB and FSP1 in protecting cells from ferroptosis do not overlap

An N-terminal amphipathic helix binds Phosphoinositides and enhances Kalirin Sec14 domain-mediated membrane interactions

8.3 Neurotrophic factor delivery Neurotrophic factors are crucial proteins that support neurons growth, survival, and differentiation