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Tibes R, Giles F, McQueen T, Bergstrom DA, Freedman SJ, Andreeff M

10.1177/1759720X221085952 115 KimJ

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The activation of AMPK broadly suppresses proinflammatory signaling pathways, including the JAK-STAT, NF-B, C/EBP, CHOP, and HIF-1 pathways, which in turn inhibits the expansion and immunosuppressive function of myeloid-derived suppressor cells (MDSCs) 42