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With the increasing popularity of MCT supplementation and growing public awareness of its potential cognition-enhancing effects, more research is needed to clarify the long-term effects of MCT supplementation on cardiovascular and metabolic health, as well as how MCTs are being used outside clinical settings

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However, there is compelling evidence that caspase-3 and caspase-8 are downstream effectors of the Fas cell death signaling pathway, indicating their importance for extrinsic Fas-mediated eryptosis (see the Extrinsic Fas-mediated eryptosis section) [130, 136]

Kaliyaperumal et al., 2025c)

In the present study, we show that depletion of cellular GSH by BSO sensitizes antihormone-resistant MCF-7:2A cells to estradiol-induced apoptosis that is mediated, in part, by the mitochondrial pathway and also activation of the c-Jun N-terminal kinase (JNK) signaling pathway