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35 Specifically, compounds like 1,3-Dioxolane and Cyclobutyl tridecyl phthalate demonstrated distinct LD 50 values, reinforcing the need for thorough toxicity evaluations in the development of new antimicrobial agents

J Mater Sci Mater Electron 29:1148211488

Thus, Nrf2 activators are expected to emerge as first-in-class innovative medicine for kidney disease treatment

Since MTX induces oxidative stress by increasing reactive oxygen species in tissues (Reference Jahovic, Cevik and Sehirli38,Reference Moghadam, Tutunchi and Namvaran-Abbas-Abad40,Reference Olayinka, Ore and Adeyemo43) , the effects of various antioxidant substances against MTX-induced oxidative stress have been investigated (Reference Savran, Cicek and Doguc7,Reference Jahovic, Cevik and Sehirli38,Reference Olayinka, Ore and Adeyemo43Reference Yuksel, Yuksel and Yagmurca45)

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