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Neurology 68, 12051212

The principal theoretical concern relates to copper

The specific functions of each component are as follows: GCL is composed of a heavy chain (GCLC) and a light chain (GCLM)

Acknowledgments The authors thank Dimitry Lapage for his guidance on animal feeding experiment and Anneke Ovyn for her guidance on the parameter test in the laboratory

Superoxide anion radical (O 2 ) is the primary cell-generated ROS which triggers a cascade of reactions and, therefore, the formation of secondary ROS, either directly or via enzymatic and metal-catalyzed processes, counting on the cell compartment