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Similarly, quail models with endogenous gout induced by a high-purine diet were treated with rutinum for 10 days

Kirchhoff S

Additionally, OLES-25%HYT downregulated pro-inflammatory cytokines and the apoptotic gene Bax, while upregulating the anti-apoptotic gene Bcl2, demonstrating its intestinal anti-inflammatory, antioxidant, and anti-apoptotic effects in experimental ulcerative colitis models