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Description

Formononetin, an isoflavone, not only inhibits degranulation of mast cells and basophils but also directly suppresses IgE production by human peripheral blood mononuclear cells through modulation of the JAK/STAT/PI3K-Akt signaling pathway, thereby attenuating allergic responses (127)

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Am J Physiol Cell Physiol 287:C327-C335 Breyer J, Samarin J, Rehm M, Lautscham L, Fabry B, Goppelt-Struebe M (2012) Inhibition of Rho kinases increases directional motility of microvascular endothelial cells

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In addition, in vitro experiments on Slc38a3 transfected oocytes revealed that depression Slc38a3-mediated glutamine transport engages direct interaction of ammonium ions with the Slc38a3 protein moiety (Hamdani et al., 2021)

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