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Shintoku R, Takigawa Y, Yamada K, Kubota C, Yoshimoto Y, Takeuchi T, et al

These findings emphasize the importance of counseling patients about possible small increased risks, particularly regarding ovarian cancer and BOTs (62)

At Month 12, the mean change from baseline in ALP for patients with cirrhosis on seladelpar was -121.4 U/L vs 23.2 U/L for placebo, and -134.8 U/L for seladelpar vs -18.0 U/L for placebo in patients without cirrhosis

TM6 and TM7 of ghrelin receptor adopt nearly identical conformations to G q -coupled 5-HT 2A receptor and G 11 -coupled M1 receptor (Supplementary Fig