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For metabolic health and insulin resistance, the evidence supports a moderate dose approach in the 5 mg range, dosed five times per week, combined with a structured exercise program

10.1074/jbc.M102341200 63 KatoH.TakemotoD.KawakitaK

Some researchers estimate that healthy adults who weigh approximately 70kg need between 8003,000mg of lysine per day, with daily doses of up to 3g shown to be generally well-tolerated