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All models included sex (male serving as reference) and age as fixed effect predictors

This lets researchers isolate the effect of each variable independently

No clinically relevant findings were observed for laboratory parameters, vital signs or ECG

[11] [4] Preclinical studies have suggested that combining amylin receptor agonism with GLP-1based therapies produces greater reductions in food intake and body weight than either approach in isolation, and early clinical data from the CagriSema programme (cagrilintide combined with semaglutide) has provided some supporting evidence in humans