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[Abstract]2026 May 30

Additionally, NPs can release medications for a prolonged period, ensuring targeted delivery to specific tissues

The activation of these inflammatory pathways is often accompanied by increased expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2), further promoting liver injury (Vangaveti et al

It promotes healing by supporting cell migration to injured areas and aiding the regeneration of damaged tissue, particularly in muscles, tendons, and ligaments

Accordingly, for clinical-stage PROTACs, selectivity is more appropriately understood primarily at the levels of target engagement and degradation profile, whereas strict cell-type selectivity is not generally considered an intrinsic property