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The importance of folate in remethylation and for Hcy level is well known ( Reference Taes, Delanghe and De Bacquer 7 , Reference Huang, Hsu and Lin 8 )

The pathogenic targeting of lysosome acidification, and particularly the V0a1 v-ATPase subunit, extends beyond AD-related conditions to mechanisms underlying the pathogenic actions of causal genes in a host of other neurodegenerative diseases 95 (Figs

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GH and IGF-I as therapeutic agents for osteoporosis