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This might include people with a history of low B12 levels on blood work, those taking metformin or proton pump inhibitors that deplete B12, vegetarians or vegans with limited dietary B12 intake, individuals with absorption issues from gastric conditions, or anyone experiencing the pronounced fatigue that often accompanies early tirzepatide therapy

Vegetarians and Vegans : Since vitamin B12 is primarily found in animal products, those following plant-based diets are at increased risk of deficiency

These cognitive symptoms often worsen throughout the day and improve slightly after rest

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