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falciparum exists in an open confirmation, the incorporation of EXP2 into membranes would need to be regulated to permit nutrient exchange only at the PVM

The hydroxyl group bound to the carbon to which R1 and R2 are attached in the compound of formula (XXIII-1) may be converted to L1-Z1-, and/or the hydroxyl group bound to the carbon to which Rx and Ry are attached may be converted to L2-Z2

Quadros EV, Lai SC, Nakayama Y, Sequeira JM, Hannibal L, Wang S, Jacobsen DW, Fedosov S, Wright E, Gallagher RC et al

A suite of highly reactive lipid aldehyde species are generated during the progression of lipid peroxidation cascades induced under conditions of OS