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2 Elevated levels of LPA, specifically unsaturated long chain acyl-LPA species, have been detected within atherosclerotic plaques and are correlated with increased expression of LPARs and dysregulated levels of enzymes that regulate LPA metabolism

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The most common type of gallstone is called cholesterol stone which makes up 90-95% of known gallstone cases

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Furthermore, an I53-50NP-based COVID-19 vaccine was recently approved in South Korea after successful completion of phase 1 and phase 3 studies providing a clear translational path forward for an HCV vaccine based on this platform 103