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The underlying mechanisms of bioactive ingredients extracted from TCM in the treatment of BC Bioactive ingredients derived from TCM, including pachymic acid, formononetin, and coptisine, have identified with encouraging anti-cancer activities, which could affect BC cell apoptosis, autophagy, ferroptosis, cell cycle, proliferation, migration, invasion, epithelialmesenchymal transition (EMT), angiogenesis, and host immunity by regulating multiple signaling pathways

Notably, the upregulation of ZIP14 and FPN acts a significant role in this process[143]

Similar to plants, the human body is constantly exposed to oxidants and/or free radicals generated during physiological processes such as mitochondrial respiration

Conclusion: Preoperative visits were associated with reduced risk of postoperative mortality in patients with cirrhosis, and greatest risk reduction was observed in patients with both PCP + GI/Hep visits

Research indicates that 4-OHE2 inhibits the binding of E2 to ERs and competitively reduces the activity of 2-OHE2 [114], potentially hindering the production of protective 2-ME2