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HOMA2-IR has an inverse correlation with serum 25(OH) vitamin D levels, and vitamin D supplementation can significantly improve insulin resistance in vitamin D-deficient individuals, particularly when daily doses are used instead of large bolus doses

At the hormonal level, ketogenesis is strongly regulated by insulin, as it inhibits the breakdown of stored fats in adipocytes and promotes glucose uptake and utilization, leading to elevated levels of inhibitors of fatty acid oxidation and KBs production, such as succinyl-CoA and malonyl-CoA (Johnston and Alberti, 1982)

On the day 27th of postnatal development, animals of both genders were divided into 2 equal subgroups which from that time, for the next 33 days, were fed either with the ketogenic or standard laboratory fodder

[DOI] [PubMed] [Google Scholar] 77.Bansal V.K., Rajan K., Sharma A., et al

Therefore, the identification of new drugs for this disease is indispensable