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Description

In addition, CTN induced ferroptosis of human liver cancer HepG2 cells by significantly enhancing ROS accumulation, reducing GSH level, and downregulating the xCT and GPX4 expression, which could be inhibited by ferrostatin-1 (Fer-1, ferroptosis inhibitor) (Liu JL

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A new successful systemic treatment is immunotherapy with immune checkpoint inhibitors, but new tumor-specific biomarkers are needed to improve patient outcomes

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