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Description

Int J Cardiol 2017;231:137-42

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FIGURE 3 Due to lack of oxygen, hypoxia leads to inhibition of prolyl hydroxylase, which is also referred as prolyl hydroxylase domain (PHD) protein

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Existing treatment strategies involve administration of high doses of 5-formyl-THF (folinic acid) in order to deliver sufficient folate to the brain to sustain neural development

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