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Evidence indicates that in some healthy individuals, high doses of NAC (2,800 mg a day) can act as a pro-oxidant rather than an antioxidant, actually lowering levels of glutathione rather than increasing them

Carcinogenesis, Mutagenesis, Impairment of Fertility:Long term studies in animals to evaluate carcinogenic potential have not been done

doi: 10.1111/j.1574-6968.2006.00370.x, PMID: [DOI] [PubMed] [Google Scholar] Maertens J

Additionally, by increasing the activity of antioxidant enzymes and inhibiting microglial activation, they regulate oxidative stress and neuroinflammation

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