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In lesional skin, excessive accumulation of ROS compromises the epidermal barrier, facilitates TEWL and allergen penetration, activates pro-inflammatory signaling cascades, and disrupts immune homeostasis (Raimondo et al., 2023)

However, it should be noted that when using these substances, scientific and reasonable principles should be followed to avoid adverse reactions caused by excessive use

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The GST-tagged WT T6B and mut T6B were eluted in freshly made 10 ml of GST-B buffer (20 mM Tris, pH 8.0, and 10 mM glutathione [G4251