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Perhaps most notably, a basolateral transporter responsible for the efflux of ergothioneine in polarised cells such as enterocytes and proximal tubules cells of the liver has yet to be identified

10.1007/s11274-016-2124-2 56 KardaniA.SoltaniA.SewellR

RPE degeneration could lead to reduction of the choriocapillaris vascular area and more vasoconstriction in the areas devoid of RPE (McLeod et al., 2009)

However, challenges remain, including variability in assay standardization, limited disease specificity for certain markers, and uncertainty around predictive thresholds and clinical interpretation, particularly in asymptomatic individuals

Rice DC , Morris SM, Sarr MG, Farnell MB, van Heerden JA, Grant CS, Rowland CM, Ilstrup DM, Donohue JH