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Pernicious anemia is a B12 deficiency anemia caused by the lack of intrinsic factor.[ref] What causes the lack of intrinsic factor in pernicious anemia

Choosing between the two depends on whether your priority is deeper support for the body or quicker symptom relief

While B12 has very low toxicity as a water-soluble vitamin with excess typically excreted in urine, rare adverse reactions can occur

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Vitamin injections are generally considered safe and well-tolerated