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doi: 10.3390/life11030222 103 GriguerCEOlivaCR

Rapamycin prevents early steps of the development of diabetic nephropathy in rats

Whereas, GA (Group IV) pretreatment significantly prevented ISO-induced overexpression of TNF-, IL-6, NF-B, COX-2 and iNOS in rat cardiac tissue (Figure 5A,B)

In rat models of chronic abdominal pain (CAP), microglia-mediated engulfment of postsynaptic spines was increased (128)

Clinically, DCD manifests as acquired cognitive and behavioral deficits that impair patients self-management capacity and treatment adherence, further accelerating disease progression (126)