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However, the requestor (manufacturer of Larsucosterol) also indicated that epigenetic therapy is currently being studied to address various types of acute and chronic organ injury and provided information related to its AHFIRM ( A lcohol-associated H epatitis to evaluate sa F ety and eff I cacy of La R sucosterol (DUR-928) treat M ent) Phase 2b study for patients diagnosed with alcoholic hepatitis

Hepatocyte cytotoxicity significantly increased with ITZ concentration ( P 30 metabolites in humans (31)

Factors responsible for the induction of ferroptosis may directly or indirectly affect glutathione peroxidases

Clark, B

doi: 10.1152/ajpcell.1992.263.6.C1181